Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1)

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CD159a; CD159-A; KLR-C1; NKG2-A; NKG2-B; NKG2-1/B Activating NK Receptor; CD159 antigen-like family member A; NK cell receptor A

Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1)

NKG2 also known as CD159a (Cluster of Differentiation 159a) is an activating receptor for natural killer cells.The protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily C, Member 1 (KLRC1) ELISA Kit Customized Service Offer
  1. "DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells."J. Exp. Med. 173:1017-1020(1991) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic structure, chromosome location, and alternative splicing of the human NKG2A gene."Immunogenetics 44:286-291(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Sequence analysis of a 62-kb region overlapping the human KLRC cluster of genes."Genomics 49:193-199(1998) [PubMed] [Europe PMC] [Abstract]
  4. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition."Immunity 27:900-911(2007) [PubMed] [Europe PMC] [Abstract]
  7. "CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence."J. Exp. Med. 205:725-735(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Structural basis for NKG2A/CD94 recognition of HLA-E."Proc. Natl. Acad. Sci. U.S.A. 105:6696-6701(2008) [PubMed] [Europe PMC] [Abstract]