Amyloid Beta Peptide 1-42 (Ab1-42)

One of the hallmarks of Alzheimer's disease is the self-aggregation of the amyloid β peptide (Aβ) in extracellular amyloid fibrils. Aβ is a peptide composed of 40 to 42 (43) amino acids, and is said to be cleaved out of the precursor protein APP by the action of β- or γ-secretase.In addition, the presence of numerous variant A β molecules has been demonstrated in the culture fluid of mouse neuroblastoma cells transfected with cDNA coding human amyloid precursor protein (APP). Among the different forms of Aβ, the 42-residue fragment (Aβ1-42) readily self-associates and forms nucleation centers from where fibrils can quickly grow. The strong tendency of Aβ1-42 to aggregate is one of the reasons for the scarcity of data on its fibril formation process. Aβ1-40 is the most common form secreted from cultured cells and found in cerebro-spinal fluid (CSF). Aβ1-42 is the major component of senile plaques and considered as the most crucial factor in AD pathogenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA946Hu21 OVA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Hu11 BSA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Hu31 KLH Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Hu22 OVA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Hu12 BSA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
SPA946Hu02 Synthetic Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; Blocking Peptide.
Antibodies MAA946Hu21 Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
PAA946Hu08 Polyclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
MAA946Mi21 Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
MAA946Mi22 Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
MAA946Hu22 Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
Assay Kits CEA946Hu ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA946Hu High Sensitive ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA946Mi ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA946Mu11 BSA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Mu21 OVA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Mu31 KLH Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
SPA946Mu01 Synthetic Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; Blocking Peptide.
Antibodies n/a Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) Polyclonal Antibody Customized Service Offer
Assay Kits CEA946Mu ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA946Mi ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA946Ra11 BSA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Ra21 OVA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Ra31 KLH Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
Antibodies PAA946Ra01 Polyclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
LAA946Ra71 Biotin-Linked Polyclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC.
Assay Kits CEA946Ra ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA946Mi ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA946Ge21 OVA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
Antibodies MAA946Ge21 Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
MAA946Ge28 Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) ELISA Kit Customized Service Offer