25-Hydroxyvitamin D3 (HVD3)

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25-HVD3; 25HVD3; Calcifediol; Calcidiol; H-VD3; 25-Hydroxycholecalciferol; 25-Hydroxy Vitamin D3; 25(OH)D

25-Hydroxyvitamin D3 (HVD3)

Calcifediol is a prehormone which is produced by hydroxylation of vitamin D3 (cholecalciferol) in the liver. Calcidiol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.

In medicine, blood concentration of calcidiol is considered the best indicator of vitamin D status. It is the most sensitive measure, though experts have called for improved standardization and reproducibility across different laboratories. The normal range varies widely depending on several factors, including age and geographic location. A broad reference range of 20–150 nmol/L has been suggested, while several studies have defined levels below 80 nmol/L as indicative of vitamin D deficiency.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA915Ge11 BSA Conjugated 25-Hydroxyvitamin D3 (HVD3) Immunogen; SDS-PAGE; WB.
CPA915Ge21 OVA Conjugated 25-Hydroxyvitamin D3 (HVD3) Immunogen; SDS-PAGE; WB.
Antibodies PAA915Ge01 Polyclonal Antibody to 25-Hydroxyvitamin D3 (HVD3) WB; IHC; ICC; IP.
LAA915Ge71 Biotin-Linked Polyclonal Antibody to 25-Hydroxyvitamin D3 (HVD3) WB; IHC; ICC.
MAA915Ge21 Monoclonal Antibody to 25-Hydroxyvitamin D3 (HVD3) WB; IHC; ICC; IP.
Assay Kits CEA915Ge ELISA Kit for 25-Hydroxyvitamin D3 (HVD3) Enzyme-linked immunosorbent assay for Antigen Detection.