Calcitonin Gene Related Peptide (CGRP)

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CALCB; CGRP2; CALC2; CGRP-II; Calcitonin Gene Related Peptide 2; Calcitonin 2; Calcitonin Related Polypeptide Beta

Calcitonin Gene Related Peptide (CGRP)

CGRP is an important cutaneous neuropeptide. It is widely expressed in both the central and peripheral nervous system. CGRP is known as pro inflammatory factor and is thought to be involved in neurogenic inflammation. It was reported that CGRP stimulate the adhesiveness of human umbilical vein endothelial cells for monocytic cell line and neutrophils.The function of CGRP in skin remains unclear. However, evidences suggested that it may be directly involved in modulating the functions of keratinocytes, Langerhans cells and microvascular endothelial cells in the skin.On the other hand, psoriasis is generally known as inflammatory and proliferative skin disorder. In psoriatic plaque lesion there are epidermal influx of polymorphonulear leukocytes, and the presence of mononuclear infiltration in the papillary dermis and in the epidermis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA876Hu01 Recombinant Calcitonin Gene Related Peptide (CGRP) Positive Control; Immunogen; SDS-PAGE; WB.
CPA876Hu21 OVA Conjugated Calcitonin Gene Related Peptide (CGRP) Immunogen; SDS-PAGE; WB.
Antibodies PAA876Hu01 Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) WB; IHC; ICC; IP.
MAA876Hu22 Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) WB; IHC; ICC; IP.
LAA876Hu71 Biotin-Linked Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) WB; IHC; ICC.
Assay Kits CEA876Hu ELISA Kit for Calcitonin Gene Related Peptide (CGRP) Enzyme-linked immunosorbent assay for Antigen Detection.
CCA876Hu CLIA Kit for Calcitonin Gene Related Peptide (CGRP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA876Mu01 Recombinant Calcitonin Gene Related Peptide (CGRP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA876Mu02 Recombinant Calcitonin Gene Related Peptide (CGRP) Positive Control; Immunogen; SDS-PAGE; WB.
CPA876Mu21 OVA Conjugated Calcitonin Gene Related Peptide (CGRP) Immunogen; SDS-PAGE; WB.
Antibodies PAA876Mu01 Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) WB; IHC; ICC; IP.
PAA876Mu02 Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) WB; IHC; ICC; IP.
Assay Kits CEA876Mu ELISA Kit for Calcitonin Gene Related Peptide (CGRP) Enzyme-linked immunosorbent assay for Antigen Detection.
CCA876Mu CLIA Kit for Calcitonin Gene Related Peptide (CGRP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA876Ra01 Recombinant Calcitonin Gene Related Peptide (CGRP) Positive Control; Immunogen; SDS-PAGE; WB.
CPA876Ra21 OVA Conjugated Calcitonin Gene Related Peptide (CGRP) Immunogen; SDS-PAGE; WB.
Antibodies PAA876Ra01 Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) WB; IHC; ICC; IP.
MAA876Ra21 Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) WB; IHC; ICC; IP.
Assay Kits CEA876Ra ELISA Kit for Calcitonin Gene Related Peptide (CGRP) Enzyme-linked immunosorbent assay for Antigen Detection.
CCA876Ra CLIA Kit for Calcitonin Gene Related Peptide (CGRP) Chemiluminescent immunoassay for Antigen Detection.
  1. "Structure and expression of the human calcitonin/CGRP genes."FEBS Lett. 209:97-103(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A second human calcitonin/CGRP gene."FEBS Lett. 183:403-407(1985) [PubMed] [Europe PMC] [Abstract]
  5. "Identification in the human central nervous system, pituitary, and thyroid of a novel calcitonin gene-related peptide, and partial amino acid sequence in the spinal cord."J. Biol. Chem. 262:542-545(1987) [PubMed] [Europe PMC] [Abstract]
  6. "Isolation, purification and characterization of beta-hCGRP from human spinal cord."Biochem. Biophys. Res. Commun. 167:993-1000(1990) [PubMed] [Europe PMC] [Abstract]
  7. "Isolation and characterization of peptides which act on rat platelets, from a pheochromocytoma."Biochem. Biophys. Res. Commun. 185:134-141(1992) [PubMed] [Europe PMC] [Abstract]