C4 Binding Protein Beta (C4BPb)

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C4BP-B; C4-BP; Complement Component 4 Binding Protein, Beta

C4 Binding Protein Beta (C4BPb)
  • C4BPB cDNA probe to isolate and characterize a genomic DNA fragment that included the murine C4BPB gene. They found that it is present in single copy and maps close to the murine homolog of C4BPA on chromosome 1. However, in several inbred strains of Mus musculus and in Mus spretus, they demonstrated 2 inphase stop codons that are incompatible with the expression of a functional C4BPB polypeptide. It appeared that the loss of a functional C4BPB gene was a relatively recent event in the evolution of the mouse. Since the genetic change had become fixed, the mice lacking the C4BPB polypeptide may have enjoyed some kind of selective advantage.there are 7 genes in the regulator of complement activation (RCA) gene cluster: C4BPA, C4BPB, MCP, CR1, CR2, DAF, and CFH. Hillarp et al.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA761Hu01 Recombinant C4 Binding Protein Beta (C4BPb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA761Hu01 Polyclonal Antibody to C4 Binding Protein Beta (C4BPb) WB; IHC; ICC; IP.
LAA761Hu71 Biotin-Linked Polyclonal Antibody to C4 Binding Protein Beta (C4BPb) WB; IHC; ICC.
LAA761Hu81 FITC-Linked Polyclonal Antibody to C4 Binding Protein Beta (C4BPb) WB; IHC; ICC; IF.
MAA761Hu21 Monoclonal Antibody to C4 Binding Protein Beta (C4BPb) WB; IHC; ICC; IP.
Assay Kits SEA761Hu ELISA Kit for C4 Binding Protein Beta (C4BPb) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA761Hu CLIA Kit for C4 Binding Protein Beta (C4BPb) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C4 Binding Protein Beta (C4BPb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C4 Binding Protein Beta (C4BPb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C4 Binding Protein Beta (C4BPb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C4 Binding Protein Beta (C4BPb) CLIA Kit Customized Service Offer
n/a ELISA Kit for C4 Binding Protein Beta (C4BPb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant C4 Binding Protein Beta (C4BPb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to C4 Binding Protein Beta (C4BPb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to C4 Binding Protein Beta (C4BPb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for C4 Binding Protein Beta (C4BPb) CLIA Kit Customized Service Offer
n/a ELISA Kit for C4 Binding Protein Beta (C4BPb) ELISA Kit Customized Service Offer
  1. "The human C4b-binding protein beta-chain gene."J. Biol. Chem. 268:15017-15023(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning of cDNA coding for the beta chain of human complement component C4b-binding protein: sequence homology with the alpha chain."Proc. Natl. Acad. Sci. U.S.A. 87:1183-1187(1990) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."Proteomics 4:454-465(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  7. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]