Toll Like Receptor 4 (TLR4)

TLR 4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA753Hu01 Recombinant Toll Like Receptor 4 (TLR4) Positive Control; Immunogen; SDS-PAGE; WB.
CPA753Hu21 OVA Conjugated Toll Like Receptor 4 (TLR4) Immunogen; SDS-PAGE; WB.
RPA753Hu02 Recombinant Toll Like Receptor 4 (TLR4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA753Hu01 Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
MAA753Hu22 Monoclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
LAA753Hu71 Biotin-Linked Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC.
PAA753Hu08 Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
PAA753Hu02 Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
LAA753Hu72 Biotin-Linked Monoclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC.
MAA753Hu21 Monoclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
Assay Kits SEA753Hu ELISA Kit for Toll Like Receptor 4 (TLR4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA753Mu01 Recombinant Toll Like Receptor 4 (TLR4) Positive Control; Immunogen; SDS-PAGE; WB.
RPA753Mu02 Recombinant Toll Like Receptor 4 (TLR4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA753Mu01 Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
LAA753Mu71 Biotin-Linked Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC.
LAA753Mu81 FITC-Linked Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IF.
PAA753Mu02 Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
Assay Kits SEA753Mu ELISA Kit for Toll Like Receptor 4 (TLR4) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA753Mu CLIA Kit for Toll Like Receptor 4 (TLR4) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA753Ra01 Recombinant Toll Like Receptor 4 (TLR4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA753Ra01 Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
LAA753Ra71 Biotin-Linked Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC.
LAA753Ra81 FITC-Linked Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IF.
MAA753Ra21 Monoclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
Assay Kits SEA753Ra ELISA Kit for Toll Like Receptor 4 (TLR4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Toll Like Receptor 4 (TLR4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Toll Like Receptor 4 (TLR4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Toll Like Receptor 4 (TLR4) Polyclonal Antibody Customized Service Offer
Assay Kits SEA753Po ELISA Kit for Toll Like Receptor 4 (TLR4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA753Bo01 Recombinant Toll Like Receptor 4 (TLR4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA753Bo01 Polyclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
MAA753Bo21 Monoclonal Antibody to Toll Like Receptor 4 (TLR4) WB; IHC; ICC; IP.
Assay Kits SEA753Bo ELISA Kit for Toll Like Receptor 4 (TLR4) Enzyme-linked immunosorbent assay for Antigen Detection.
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  16. ErratumNat. Commun. 3:653-653(2012)
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  24. "Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration."Hum. Mol. Genet. 14:1449-1455(2005) [PubMed] [Europe PMC] [Abstract]