8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a)

The isoprostanes are a family of eicosanoids of non-enzymatic origin produced by the random oxidation of tissue phospholipids by oxygen radicals. Isoprostanes appear as artifacts in tissue and plasma samples which have undergone oxidative degradation during prolonged or improper storage. They also appear in the plasma and urine under normal conditions and are elevated by oxidative stress. At least one of the isoprostanes, 8-isoprostane (8-epi PGF2α), has been shown to have biological activity. It is a potent pulmonary and renal vasoconstrictor1 and has been implicated as a causative mediator of hepatorenal syndrome and pulmonary oxygen toxicity.2 8-Isoprostane has been proposed as a marker of antioxidant deficiency and oxidative stress and elevated levels have been found in heavy smokers.3 8-Isoprostane levels are also a relative indicator of sample integrity for lipid-containing samples such as serum, plasma, and whole cell preparations.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) Polyclonal Antibody Customized Service Offer
Assay Kits CEA701Ge ELISA Kit for 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) Enzyme-linked immunosorbent assay for Antigen Detection.