Endostatin (ES)

Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors Endostatin is a natural antiangiogenic protein that has been shown to inhibit the growth of blood vessels, thereby starving cancerous tumors. In preclinical studies, the repeated administration of Endostatin consistently shrank primary tumors and, unlike traditional chemotherapy, showed no drug resistance over time.Endostatin is currently being studied as part of cancer research.In a Phase I clinical trial of Endostatin of the 19 patients treated, 12 were switched out of the trial by their physicians due to continued progression of their disease.In a Phase II clinical trial of Endostatin forty two patients with pancreatic endocrine tumors or carcinoid tumors were treated.A phase III clinical trial was carried out on 493 histology or cytology confirmed stage IIIB and IV NSCLC patients with a life expectancy >3 months.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA542Hu31 KLH Conjugated Endostatin (ES) Immunogen; SDS-PAGE; WB.
EPA542Hu61 Eukaryotic Endostatin (ES) Positive Control; Immunogen; SDS-PAGE; WB.
APA542Hu61 Active Endostatin (ES) Cell culture; Activity Assays.
Antibodies PAA542Hu01 Polyclonal Antibody to Endostatin (ES) WB; IHC; ICC; IP.
PAA542Hu06 Polyclonal Antibody to Endostatin (ES) WB; IHC; ICC; IP.
Assay Kits SEA542Hu ELISA Kit for Endostatin (ES) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA542Hu ELISA Kit for Endostatin (ES) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Endostatin (ES) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Endostatin (ES) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endostatin (ES) Polyclonal Antibody Customized Service Offer
Assay Kits SEA542Mu ELISA Kit for Endostatin (ES) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA542Ra01 Recombinant Endostatin (ES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Endostatin (ES) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endostatin (ES) Polyclonal Antibody Customized Service Offer
Assay Kits CEA542Ra ELISA Kit for Endostatin (ES) Enzyme-linked immunosorbent assay for Antigen Detection.