Cystatin A (CSTA)

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Cys-A; STF1; STFA; Stefin A; Cystatin-AS

Cystatin A (CSTA)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L.

The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA476Hu01 Recombinant Cystatin A (CSTA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA476Hu01 Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC; IP.
MAA476Hu22 Monoclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC; IP.
LAA476Hu71 Biotin-Linked Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC.
LAA476Hu81 FITC-Linked Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC; IF.
Assay Kits SEA476Hu ELISA Kit for Cystatin A (CSTA) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA476Mu01 Recombinant Cystatin A (CSTA) Positive Control; Immunogen; SDS-PAGE; WB.
RPA476Mu02 Recombinant Cystatin A (CSTA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA476Mu01 Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC; IP.
LAA476Mu81 FITC-Linked Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC; IF.
LAA476Mu71 Biotin-Linked Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC.
PAA476Mu02 Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC; IP.
Assay Kits SEA476Mu ELISA Kit for Cystatin A (CSTA) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA476Ra01 Recombinant Cystatin A (CSTA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA476Ra01 Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC; IP.
LAA476Ra71 Biotin-Linked Polyclonal Antibody to Cystatin A (CSTA) WB; IHC; ICC.
Assay Kits SEA476Ra ELISA Kit for Cystatin A (CSTA) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA476Po01 Recombinant Cystatin A (CSTA) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Cystatin A (CSTA) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cystatin A (CSTA) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cystatin A (CSTA) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cystatin A (CSTA) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cystatin A (CSTA) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cystatin A (CSTA) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cystatin A (CSTA) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cystatin A (CSTA) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cystatin A (CSTA) ELISA Kit Customized Service Offer
  1. "Protein inhibitors of cysteine proteinases. II. Primary structure of stefin, a cytosolic protein inhibitor of cysteine proteinases from human polymorphonuclear granulocytes."Hoppe-Seyler's Z. Physiol. Chem. 364:1481-1486(1983) [PubMed] [Europe PMC] [Abstract]
  2. "Comparative studies on the primary structure of human cystatin as from epidermis, liver, spleen, and leukocytes."J. Biochem. 105:986-991(1989) [PubMed] [Europe PMC] [Abstract]
  3. "Effects of UV, 4-NQO and TPA on gene expression in cultured human epidermal keratinocytes."Nucleic Acids Res. 15:5945-5962(1987) [PubMed] [Europe PMC] [Abstract]
  4. "Genomic structure of human cystatin A."DNA Seq. 8:71-76(1997) [PubMed] [Europe PMC] [Abstract]
  5. "Structure and transcriptional regulation of the human cystatin A gene. The 12-o-tetradecanoylphorbol-13-acetate (tpa) responsive element-2 site (-272 to -278) on cystatin a gene is critical for tpa-dependent regulation."J. Biol. Chem. 273:17375-17380(1998) [PubMed] [Europe PMC] [Abstract]
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]