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This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types.
Schmitt et al. (1996) cloned a cDNA for the mouse inhibin/activin beta-C gene. The mouse gene encodes a predicted 352-amino acid prepropeptide and a 116-amino acid mature protein which is 94% identical to the human sequence. Ribonuclease protein assays showed that mouse Inhbc is mainly expressed in adult liver.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA446Hu01 | Recombinant Inhibin Beta C (INHbC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA446Hu01 | Polyclonal Antibody to Inhibin Beta C (INHbC) | WB; ICC; IHC-P; IHC-F; ELISA. |
| MAA446Hu22 | Monoclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC; IP. | |
| LAA446Hu71 | Biotin-Linked Polyclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC. | |
| LAA446Hu81 | FITC-Linked Polyclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC; IF. | |
| MAA446Hu21 | Monoclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA446Hu | ELISA Kit for Inhibin Beta C (INHbC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA446Mu01 | Recombinant Inhibin Beta C (INHbC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA446Mu02 | Recombinant Inhibin Beta C (INHbC) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA446Mu01 | Polyclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC; IP. |
| PAA446Mu02 | Polyclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA446Mu | ELISA Kit for Inhibin Beta C (INHbC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA446Ra01 | Recombinant Inhibin Beta C (INHbC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA446Ra01 | Polyclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC; IP. |
| LAA446Ra71 | Biotin-Linked Polyclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC. | |
| LAA446Ra81 | FITC-Linked Polyclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC; IF. | |
| MAA446Ra21 | Monoclonal Antibody to Inhibin Beta C (INHbC) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA446Ra | ELISA Kit for Inhibin Beta C (INHbC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Cloning of a new member of the TGF-beta family: a putative new activin beta C chain."Biochem. Biophys. Res. Commun. 206:608-613(1995) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Inhibins, activins, and follistatins: expression of mRNAs and cellular localization in tissues from men with benign prostatic hyperplasia."Prostate 34:34-43(1998) [PubMed] [Europe PMC] [Abstract]