Myelin Associated Glycoprotein (MAG)

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GMA; S-MAG; Siglec-4; SIGLEC4A; Sialic Acid Binding Ig-Like Lectin 4A

Myelin Associated Glycoprotein (MAG)

Myelin-associated glycoprotein (MAG) is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR MAG is believed to be involved in myelination during nerve regeneration.Myelin-associated glycoprotein (MAG), a membrane protein of 100 kD, is thought to be involved in the process of myelination (Barton et al., 1987). MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor (NGR, or RTN4R) (Liu et al., 2002).Spagnol et al. (1989) found that MAG cDNA clones isolated from a human brain cDNA library had an open reading frame of 1,878 nucleotides encoding a peptide of 626 amino acids with a calculated molecular weight of 69.1 kD.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA422Hu01 Recombinant Myelin Associated Glycoprotein (MAG) Positive Control; Immunogen; SDS-PAGE; WB.
RPA422Hu02 Recombinant Myelin Associated Glycoprotein (MAG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA422Hu01 Polyclonal Antibody to Myelin Associated Glycoprotein (MAG) WB; IHC; ICC; IP.
MAA422Hu22 Monoclonal Antibody to Myelin Associated Glycoprotein (MAG) WB; IHC; ICC; IP.
PAA422Hu02 Polyclonal Antibody to Myelin Associated Glycoprotein (MAG) WB; IHC; ICC; IP.
Assay Kits SEA422Hu ELISA Kit for Myelin Associated Glycoprotein (MAG) Enzyme-linked immunosorbent assay for Antigen Detection.
AEA422Hu ELISA Kit for Anti-Myelin Associated Glycoprotein Antibody (Anti-MAG) Enzyme-linked immunosorbent assay for Antibody Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myelin Associated Glycoprotein (MAG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myelin Associated Glycoprotein (MAG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myelin Associated Glycoprotein (MAG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myelin Associated Glycoprotein (MAG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myelin Associated Glycoprotein (MAG) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA422Ra01 Recombinant Myelin Associated Glycoprotein (MAG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA422Ra01 Polyclonal Antibody to Myelin Associated Glycoprotein (MAG) WB; IHC; ICC; IP.
MAA422Ra21 Monoclonal Antibody to Myelin Associated Glycoprotein (MAG) WB; IHC; ICC; IP.
Assay Kits SEA422Ra ELISA Kit for Myelin Associated Glycoprotein (MAG) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "cDNA cloning and amino acid sequence for human myelin-associated glycoprotein."Biochem. Biophys. Res. Commun. 163:1473-1480(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning of human myelin-associated glycoprotein."J. Neurosci. Res. 24:137-142(1989) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of the glycosylated sequons of human myelin-associated glycoprotein."Biochem. Biophys. Res. Commun. 197:457-464(1993) [PubMed] [Europe PMC] [Abstract]