Complement Component 5a (C5a)
  • C5a is a protein fragment released from complement component C5. In humans, the polypeptide contains 74 amino acids. NMR spectroscopy proved that the molecule is composed of four helices and loops connecting the helices. On the N terminus a short 1.5 turn helix is also present. The longest helix -IV- develops three disulfide bonds with helix II and III. C5a is rapidly metabolised by a serum enzyme, carboxypeptidase B to a 73 amino acid form, C5a des-Arg.

  • C5a binds to a receptor protein on the surface of target cells, C5aR or CD88. This is a member of the G-protein-coupled receptor superfamily of proteins, predicted to have seven transmembrane helical domains of largely hydrophobic amino acid residues, forming three intra- and three extra-cellular loops, with an extracellular N-terminus and an intracellular C-terminus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA388Hu01 Recombinant Complement Component 5a (C5a) Positive Control; Immunogen; SDS-PAGE; WB.
EPA388Hu61 Eukaryotic Complement Component 5a (C5a) Positive Control; Immunogen; SDS-PAGE; WB.
APA388Hu61 Active Complement Component 5a (C5a) Cell culture; Activity Assays.
Antibodies PAA388Hu01 Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
PAA388Hu06 Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
MAA388Hu21 Monoclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
Assay Kits SEA388Hu ELISA Kit for Complement Component 5a (C5a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA388Mu01 Recombinant Complement Component 5a (C5a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA388Mu01 Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
LAA388Mu71 Biotin-Linked Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC.
MAA388Mu21 Monoclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
LAA388Mu72 Biotin-Linked Monoclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC.
Assay Kits SEA388Mu ELISA Kit for Complement Component 5a (C5a) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA388Mu CLIA Kit for Complement Component 5a (C5a) Chemiluminescent immunoassay for Antigen Detection.
HEA388Mu High Sensitive ELISA Kit for Complement Component 5a (C5a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA388Ra01 Recombinant Complement Component 5a (C5a) Positive Control; Immunogen; SDS-PAGE; WB.
RPA388Ra02 Recombinant Complement Component 5a (C5a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA388Ra01 Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
PAA388Ra02 Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
LAA388Ra81 FITC-Linked Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IF.
LAA388Ra71 Biotin-Linked Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC.
MAA388Ra21 Monoclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
Assay Kits SEA388Ra ELISA Kit for Complement Component 5a (C5a) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA388Ra CLIA Kit for Complement Component 5a (C5a) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Complement Component 5a (C5a) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Complement Component 5a (C5a) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Complement Component 5a (C5a) Polyclonal Antibody Customized Service Offer
Assay Kits SEA388Rb ELISA Kit for Complement Component 5a (C5a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPA388Ca21 OVA Conjugated Complement Component 5a (C5a) Immunogen; SDS-PAGE; WB.
Antibodies PAA388Ca08 Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
Assay Kits SEA388Ca ELISA Kit for Complement Component 5a (C5a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA388Po01 Recombinant Complement Component 5a (C5a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA388Po01 Polyclonal Antibody to Complement Component 5a (C5a) WB; IHC; ICC; IP.
Assay Kits SEA388Po ELISA Kit for Complement Component 5a (C5a) Enzyme-linked immunosorbent assay for Antigen Detection.