Protein Kinase Inhibitor Beta (PKIb)
[Edit]PKI-B; PRKACN2; CAMP-Dependent Protein Kinase Inhibitor Beta
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cAMP-dependent protein kinase inhibitor beta is a member of the cAMP-dependent protein kinase inhibitor family. Studies of a similar protein in rat suggest that this protein may interact with the catalytic subunit of cAMP-dependent protein kinase and act as a competitive inhibitor. At least three alternatively spliced transcript variants encoding the same protein have been reported.
The deduced 70-amino acid protein has a calculated molecular mass of about 7.4 kD. The purified protein has an apparent molecular mass of 10.5 by SDS-PAGE.Using kinetic analysis for inhibitor activity, Van Patten et al. (1991) determined that purified PKIB is a competitive inhibitor of cAMP-dependent protein kinase.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA359Hu01 | Recombinant Protein Kinase Inhibitor Beta (PKIb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA359Hu01 | Polyclonal Antibody to Protein Kinase Inhibitor Beta (PKIb) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Protein Kinase Inhibitor Beta (PKIb) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Protein Kinase Inhibitor Beta (PKIb) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Protein Kinase Inhibitor Beta (PKIb) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Protein Kinase Inhibitor Beta (PKIb) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Protein Kinase Inhibitor Beta (PKIb) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Protein Kinase Inhibitor Beta (PKIb) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Protein Kinase Inhibitor Beta (PKIb) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA359Ra01 | Recombinant Protein Kinase Inhibitor Beta (PKIb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA359Ra01 | Polyclonal Antibody to Protein Kinase Inhibitor Beta (PKIb) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Protein Kinase Inhibitor Beta (PKIb) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Protein Kinase Inhibitor Beta (PKIb) | ELISA Kit Customized Service Offer |
- "Cloning and mapping of human PKIB and PKIG, and comparison of tissue expression patterns of three members of the protein kinase inhibitor family, including PKIA."Biochem. J. 349:403-407(2000) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]