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Phospholipase C Gamma 1 (PLCg1)

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NCKAP3; PLC-G1; PLC-II; PLC1; PLC148; PLCgamma1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; Phosphoinositide phospholipase C-gamma-1

Phospholipase C Gamma 1 (PLCg1)
CCC A269
HGNC 9065
MGI 97615
PubMed 24497536
RGD 3347
UniProt P19174
Wiki PLCG1

Phospholipase C, gamma 1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Researchers studying PLCg1 and its role in breast cancer metastasis discovered this gene can promote cancer metastasis and subsequently blocking it stopped cancer from spreading. Research is ongoing but this gene could lead to the development of new anti-cancer drugs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA269Hu01 Recombinant Phospholipase C Gamma 1 (PLCg1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA269Hu01 Polyclonal Antibody to Phospholipase C Gamma 1 (PLCg1) WB; IHC; ICC; IP.
MAA269Hu22 Monoclonal Antibody to Phospholipase C Gamma 1 (PLCg1) WB; IHC; ICC; IP.
Assay Kits SEA269Hu ELISA Kit for Phospholipase C Gamma 1 (PLCg1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phospholipase C Gamma 1 (PLCg1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phospholipase C Gamma 1 (PLCg1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phospholipase C Gamma 1 (PLCg1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phospholipase C Gamma 1 (PLCg1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phospholipase C Gamma 1 (PLCg1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phospholipase C Gamma 1 (PLCg1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phospholipase C Gamma 1 (PLCg1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phospholipase C Gamma 1 (PLCg1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phospholipase C Gamma 1 (PLCg1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phospholipase C Gamma 1 (PLCg1) ELISA Kit Customized Service Offer
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