Ribonuclease P (RNASEP)

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Rnase-P; RNASEP1; RPP40; Ribonuclease P/MRP 40kDa Subunit

Ribonuclease P (RNASEP)

Ribonuclease P (RNase P) is a type of Ribonuclease which cleaves RNA. RNase P is unique from other RNases in that it is a ribozyme-a ribonucleic acid that acts as a catalyst in the same way that a protein based enzyme would. Its function is to cleave off an extra, or precursor, sequence of RNA on tRNA molecules. Further RNase P is one of two known multiple turnover ribozymes in nature (the other being the ribosome), the discovery of which earned Professor Sidney Altman the Nobel Prize in Chemistry in 1989.

In fact, Sidney Altman discovered the existence of precursor tRNA with flanking sequences and was the first to characterize RNase P and its activity in processing of the 5' leader sequence of precursor tRNA back in the 70's.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA198Hu01 Recombinant Ribonuclease P (RNASEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA198Hu01 Polyclonal Antibody to Ribonuclease P (RNASEP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Ribonuclease P (RNASEP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribonuclease P (RNASEP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribonuclease P (RNASEP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribonuclease P (RNASEP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribonuclease P (RNASEP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribonuclease P (RNASEP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribonuclease P (RNASEP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA198Ra01 Recombinant Ribonuclease P (RNASEP) Positive Control; Immunogen; SDS-PAGE; WB.
APA198Ra01 Active Ribonuclease P (RNASEP) Cell culture; Activity Assays.
Antibodies PAA198Ra01 Polyclonal Antibody to Ribonuclease P (RNASEP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Ribonuclease P (RNASEP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribonuclease P (RNASEP) ELISA Kit Customized Service Offer
  1. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P."RNA 4:407-417(1998) [PubMed] [Europe PMC] [Abstract]