Collagen Type IV (COL4)

Type-IV collagen is a type of collagen found primarily in the basal lamina. The C-terminus domain is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, type-IV lacks the regular glycine in every third residue necessary for the tight, collagen helix. This makes the overall arrangement more sloppy with kinks. These two features cause the collagen to form in a sheet, the form of the basal lamina.

All of the type IV collagen in mammals is derived from six genetically distinct a-chain polypeptides (a1–a6). The type IV collagen a-chains have similar domain structures and share between 50–70% homology at the amino-acid level. The a-chains can be separated into three domains: an amino-terminal 7S domain, a middle triple-helical domain, and a carboxy-terminal globular non-collagenous (NC)-1 domain (see figure).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Collagen Type IV (COL4) Antigenic Transformation Customized Service Offer
Antibodies PAA180Hu01 Polyclonal Antibody to Collagen Type IV (COL4) WB; IHC; ICC; IP.
LAA180Hu71 Biotin-Linked Polyclonal Antibody to Collagen Type IV (COL4) WB; IHC; ICC.
Assay Kits SEA180Hu ELISA Kit for Collagen Type IV (COL4) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA180Hu CLIA Kit for Collagen Type IV (COL4) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Collagen Type IV (COL4) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Collagen Type IV (COL4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Collagen Type IV (COL4) Polyclonal Antibody Customized Service Offer
Assay Kits SEA180Mu ELISA Kit for Collagen Type IV (COL4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Collagen Type IV (COL4) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Collagen Type IV (COL4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Collagen Type IV (COL4) Polyclonal Antibody Customized Service Offer
Assay Kits SEA180Ra ELISA Kit for Collagen Type IV (COL4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Collagen Type IV (COL4) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Collagen Type IV (COL4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Collagen Type IV (COL4) Polyclonal Antibody Customized Service Offer
Assay Kits SEA180Po ELISA Kit for Collagen Type IV (COL4) Enzyme-linked immunosorbent assay for Antigen Detection.