Creatine Kinase, Muscle (CKM)

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CK-MM; CKMM; CK3; CK-M; MM-CK; M-CK; Creatine kinase M-type, N-terminally processed

Creatine Kinase, Muscle (CKM)

CKM is a cytoplasmic enzyme involved in cellular energy homeostasis. The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine and between phospho-creatine and ADP. Its functional entity is a MM-CK homodimer in striated (sarcomeric) skeletal and cardiac muscle.In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Since no other organ than cardiac muscle expresses significant levels of MB-CK, this clinical test is still fairly reliable, together with troponin-T, for diagnosing a myocardial infarction.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Hu01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Hu01 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
MAA109Hu22 Monoclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
LAA109Hu71 Biotin-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC.
Assay Kits SEA109Hu ELISA Kit for Creatine Kinase, Muscle (CKM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Mu01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
RPA109Mu02 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Mu01 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
LAA109Mu71 Biotin-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC.
LAA109Mu81 FITC-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IF.
PAA109Mu02 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
MAA109Mu21 Monoclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
LAA109Mu72 Biotin-Linked Monoclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC.
Assay Kits SEA109Mu ELISA Kit for Creatine Kinase, Muscle (CKM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Ra01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
NPA109Ra01 Native Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Ra01 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
LAA109Ra71 Biotin-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC.
MAA109Ra21 Monoclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
LAA109Ra72 Biotin-Linked Monoclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC.
Assay Kits SEA109Ra ELISA Kit for Creatine Kinase, Muscle (CKM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Rb01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Rb51 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
MAA109Rb21 Monoclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
Assay Kits SEA109Rb ELISA Kit for Creatine Kinase, Muscle (CKM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Ca01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Ca01 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Creatine Kinase, Muscle (CKM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Creatine Kinase, Muscle (CKM) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Po01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Po01 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
LAA109Po81 FITC-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IF.
LAA109Po71 Biotin-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Creatine Kinase, Muscle (CKM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Creatine Kinase, Muscle (CKM) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Bo01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Bo01 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Creatine Kinase, Muscle (CKM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Creatine Kinase, Muscle (CKM) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Ga01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Ga01 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Creatine Kinase, Muscle (CKM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Creatine Kinase, Muscle (CKM) ELISA Kit Customized Service Offer

Organism species: Danio rerio (Zebrafish)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA109Fi01 Recombinant Creatine Kinase, Muscle (CKM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA109Fi01 Polyclonal Antibody to Creatine Kinase, Muscle (CKM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Creatine Kinase, Muscle (CKM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Creatine Kinase, Muscle (CKM) ELISA Kit Customized Service Offer
  1. "Isolation and sequence analysis of a full-length cDNA for human M creatine kinase."Biochem. Biophys. Res. Commun. 140:981-989(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene."J. Biol. Chem. 263:17142-17149(1988) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Muscle creatine kinase isoenzyme expression in adult human brain."J. Biol. Chem. 265:6403-6409(1990) [PubMed] [Europe PMC] [Abstract]
  6. "cDNA cloning and mapping of the human creatine kinase M gene to 19q13."Am. J. Hum. Genet. 40:115-125(1987) [PubMed] [Europe PMC] [Abstract]
  7. "Crystallization and preliminary X-ray analysis of human muscle creatine kinase."Acta Crystallogr. D 55:669-670(1999) [PubMed] [Europe PMC] [Abstract]