Matrix Metalloproteinase 10 (MMP10)

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STMY2; SL2; Stromelysin 2; Transin-2

Matrix Metalloproteinase 10 (MMP10)

Chang et al. (2006) found that human umbilical vein endothelial cells in which HDAC7 (HDAC7A) expression was suppressed by RNA interference failed to adhere to each other. Microarray analysis showed that HDAC7 suppression led to dysregulation of numerous genes encoding extracellular matrix and adhesion proteins, including 6.5-fold upregulation of MMP10 and 8.6-fold downregulation of the MMP10 inhibitor, TIMP1.

Chang et al. (2006) found that HDAC7 downregulated MMP10 by associating with MEF2 , an MMP10 transcriptional activator. Hdac7 deletion in mice, which was embryonic lethal due to widespread vascular damage, resulted in dramatic upregulation of Mmp10 in the perivascular region and downregulation of Timp1 in endothelial cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA098Hu01 Recombinant Matrix Metalloproteinase 10 (MMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA098Hu01 Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IP.
MAA098Hu22 Monoclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IP.
LAA098Hu71 Biotin-Linked Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC.
LAA098Hu81 FITC-Linked Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IF.
Assay Kits SEA098Hu ELISA Kit for Matrix Metalloproteinase 10 (MMP10) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA098Hu CLIA Kit for Matrix Metalloproteinase 10 (MMP10) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA098Mu01 Recombinant Matrix Metalloproteinase 10 (MMP10) Positive Control; Immunogen; SDS-PAGE; WB.
RPA098Mu02 Recombinant Matrix Metalloproteinase 10 (MMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA098Mu01 Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IP.
PAA098Mu02 Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IP.
Assay Kits SEA098Mu ELISA Kit for Matrix Metalloproteinase 10 (MMP10) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA098Mu CLIA Kit for Matrix Metalloproteinase 10 (MMP10) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA098Ra01 Recombinant Matrix Metalloproteinase 10 (MMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA098Ra01 Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IP.
MAA098Ra21 Monoclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IP.
Assay Kits SEA098Ra ELISA Kit for Matrix Metalloproteinase 10 (MMP10) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA098Ra CLIA Kit for Matrix Metalloproteinase 10 (MMP10) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Matrix Metalloproteinase 10 (MMP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Matrix Metalloproteinase 10 (MMP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10) Polyclonal Antibody Customized Service Offer
Assay Kits SEA098Rb ELISA Kit for Matrix Metalloproteinase 10 (MMP10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA098Po01 Recombinant Matrix Metalloproteinase 10 (MMP10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA098Po01 Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IP.
MAA098Po21 Monoclonal Antibody to Matrix Metalloproteinase 10 (MMP10) WB; IHC; ICC; IP.
Assay Kits SEA098Po ELISA Kit for Matrix Metalloproteinase 10 (MMP10) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA098Po CLIA Kit for Matrix Metalloproteinase 10 (MMP10) Chemiluminescent immunoassay for Antigen Detection.
  1. "The collagenase gene family in humans consists of at least four members."Biochem. J. 253:187-192(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Crystal structure of the catalytic domain of human matrix metalloproteinase 10."J. Mol. Biol. 336:707-716(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]