Glycoprotein 130 (gp130)

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CDw130; CD130; IL6ST; GP130-RAPS; IR6RB; IL6R-Beta; IR6RB; IR6-RB; Interleukin 6 Signal Transducer; Oncostatin M Receptor; Interleukin-6 Receptor Subunit Beta

Glycoprotein 130 (gp130)

Glycoprotein 130 is a transmembrane protein which is the founding member of the class of all cytokine receptors. It forms one subunit of type I cytokine receptors within the IL-6 receptor family. It is often referred to as the common gp130 subunit, and is important for signal transduction following cytokine engagement.

As with other type I cytokine receptors, gp130 possesses a WSXWS amino acid motif that ensures correct protein folding and ligand binding. It interacts with Janus kinases to elicit an intracellular signal following receptor interaction with its ligand. Structurally, gp130 is composed of five fibronectin type-III domains and one immunoglobulin-like C2-type (immunoglobulin-like) domain in its extracellular portion.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA046Hu01 Recombinant Glycoprotein 130 (gp130) Positive Control; Immunogen; SDS-PAGE; WB.
RPA046Hu02 Recombinant Glycoprotein 130 (gp130) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA046Hu01 Polyclonal Antibody to Glycoprotein 130 (gp130) WB; IHC; ICC; IP.
MAA046Hu22 Monoclonal Antibody to Glycoprotein 130 (gp130) WB; IHC; ICC; IP.
PAA046Hu02 Polyclonal Antibody to Glycoprotein 130 (gp130) WB; IHC; ICC; IP.
LAA046Hu71 Biotin-Linked Polyclonal Antibody to Glycoprotein 130 (gp130) WB; IHC; ICC.
Assay Kits SEA046Hu ELISA Kit for Glycoprotein 130 (gp130) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA046Mu01 Recombinant Glycoprotein 130 (gp130) Positive Control; Immunogen; SDS-PAGE; WB.
RPA046Mu02 Recombinant Glycoprotein 130 (gp130) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA046Mu01 Polyclonal Antibody to Glycoprotein 130 (gp130) WB; IHC; ICC; IP.
PAA046Mu02 Polyclonal Antibody to Glycoprotein 130 (gp130) WB; IHC; ICC; IP.
Assay Kits SEA046Mu ELISA Kit for Glycoprotein 130 (gp130) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA046Ra01 Recombinant Glycoprotein 130 (gp130) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA046Ra01 Polyclonal Antibody to Glycoprotein 130 (gp130) WB; IHC; ICC; IP.
MAA046Ra21 Monoclonal Antibody to Glycoprotein 130 (gp130) WB; IHC; ICC; IP.
Assay Kits SEA046Ra ELISA Kit for Glycoprotein 130 (gp130) Enzyme-linked immunosorbent assay for Antigen Detection.
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