Activated Leukocyte Cell Adhesion Molecule (ALCAM)

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CD166; MEMD; Activated Leucocyte Cell Adhesion Molecule

Activated Leukocyte Cell Adhesion Molecule (ALCAM)

ALCAM/CD166 is a member of the immunoglobulin gene superfamily belonging to a subgroup with five extracellular immunoglobulin-like domains(VVC2C2C2), which includes MCAM/CD146/MUC18 and B-CAM/Lutheran. These molecules are involved in the development and maintenance of tissue architecture, neurogenesis, hematopoiesis, immune responses and tumor progression. ALCAM/CD166 mediates cell-cell clustering through homophilic (ALCAM-ALCAM) and heterophilic (ALCAM-CD6) interactions. Its pattern of expression in human tissues and cells is broad and includes epithelia, neurons, lymphoid and myeloid cells, hematopoietic and mesenchymal stem cells. The relevance of the engagement of the heterophilic pair CD166-CD6 for optimal activation of T cells has been recently demonstrated.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA002Hu01 Recombinant Activated Leukocyte Cell Adhesion Molecule (ALCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA002Hu01 Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC; IP.
MAA002Hu22 Monoclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC; IP.
LAA002Hu71 Biotin-Linked Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC.
LAA002Hu81 FITC-Linked Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC; IF.
Assay Kits SEA002Hu ELISA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA002Hu CLIA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA002Mu01 Recombinant Activated Leukocyte Cell Adhesion Molecule (ALCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA002Mu01 Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA002Ra01 Recombinant Activated Leukocyte Cell Adhesion Molecule (ALCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA002Ra01 Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC; IP.
LAA002Ra71 Biotin-Linked Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC.
LAA002Ra81 FITC-Linked Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC; IF.
Assay Kits n/a CLIA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA Kit Customized Service Offer

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA002Rb01 Recombinant Activated Leukocyte Cell Adhesion Molecule (ALCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA002Rb51 Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA002Bo01 Recombinant Activated Leukocyte Cell Adhesion Molecule (ALCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA002Bo01 Polyclonal Antibody to Activated Leukocyte Cell Adhesion Molecule (ALCAM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA Kit Customized Service Offer
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  3. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
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  9. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  10. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
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  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Molecular model of the N-terminal receptor-binding domain of the human CD6 ligand ALCAM."Protein Sci. 4:1644-1647(1995) [PubMed] [Europe PMC] [Abstract]